PRECISION-TBI
A multi-centre prospective observational cohort study of patients with moderate to severe traumatic brain injury.
What is the aim of the study: Traumatic Brain Injury is a devastating condition and a leading cause of death and long-term disability, particularly in young adults. PRECISION_TBI focuses on the most severe types of TBI that require hospital management and ICU care – moderate to severe TBI (m-sTBI). The fact that every patient with m-sTBI is different, has a different type of injury and is treated differently from hospital to hospital makes it very difficult to study m-sTBI and identify the most effective treatments for improving patient outcomes.
This study will be able to statistically identify which treatments are most strongly associated with better patient outcomes. These treatments can then be considered as candidate interventions in future research studies. Recovery at 6 months after injury will be collected for all enrolled participants allowing us to better understand how different injuries and treatments have affected long term patient outcomes. The data collected will also allow hospitals to track progress over time and identify how changes to management protocols and care systems may result in better outcomes for patients in this highly vulnerable group.
Who can participate:
Inclusion criteria:
-Adult patients (age ≥18 years)-Clinical diagnosis of moderate to severe TBI
-Admitted to the ICU with a moderate to severe TBI requiring invasive neuromonitoring as per the treating clinical team
-Recruited within 48 hours of ICU admission
Exclusion criteria:
-Admission to the ICU is solely for the purposes of palliative care or confirmation of organ donation.
-Advanced care directive or previously stated wish not to be included in research activities.
Further information
Visit the PRECISION TBI website by clicking here.